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Items: 11

1.

A UTX–MLL4–p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription (RNA-Seq)

(Submitter supplied) Enhancer activation is a critical step for gene activation. Here we report a novel epigenetic crosstalk at enhancers between the UTX (H3K27 demethylase)-MLL4 (H3K4 methyltransferase) complex and the histone acetyltransferase p300. We demonstrate that UTX, in a demethylase activity-independent manner, facilitates conversion of naïve (unmarked) enhancers in embryonic stem cells to an active (H3K4me1+/H3K27ac+) state by recruiting and coupling the enzymatic functions of MLL4 and p300. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
9 Samples
Download data: TXT
Series
Accession:
GSE97702
ID:
200097702
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

MLL4KD_JM8A-9234-3_AGTCAA_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575708
ID:
302575708
4.

MLL4KD_JM8A-9234-2_GAGTGG_L001_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575707
ID:
302575707
5.

MLL4KD_JM8A_9234-1_GGCTAC_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575706
ID:
302575706
6.

UTXKO_A6-3_GCCAAT_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575705
ID:
302575705
7.

UTXKO_A6-2_GATCAG_L001_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575704
ID:
302575704
8.

UTXKO_A6-1_ACTTGA_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575703
ID:
302575703
9.

UTXWT_JM8A-3_ACAGTG_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575702
ID:
302575702
10.

UTXWT_JM8A-2_TTAGGC_L001_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575701
ID:
302575701
11.

UTXWT_JM8A-1_ATCACG_L002_R1_001

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL13112
Series:
GSE97702 GSE97703
Download data
Sample
Accession:
GSM2575700
ID:
302575700
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Supplemental Content

db=gds|term=GSE97702[Accession]|query=1|qty=2|blobid=MCID_674f9bc52ced8a147a2a7524|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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