GSM1001861[Accession] - GEO DataSets

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Items: 4

Select item 2000407951.

Transcriptomic Dose Response Changes in Female Mouse and Rat Lungs following Chloroprene Exposure

(Submitter supplied) ß-chloroprene (2-chloro-1,3-butadiene), a monomer used in the production of neoprene elastomers, is of regulatory interest due to the production of multi-organ tumors in mouse and rat cancer bioassays. A significant increase in female mouse lung tumors was observed at the lowest exposure concentration of 12.8 ppm while a small, but not statistically significant, increase was observed in female rats only at the highest exposure concentration of 80 ppm. more...

Organism:: Mus musculus; Rattus norvegicus

Type:: Expression profiling by array

Datasets:: GDS4847 GDS4848
Platforms:: GPL1355 GPL1261
100 Samples

Download data: CEL

Series

Accession:: GSE40795

ID:: 200040795

Select item 48482.

Chloroprene effect on rat lung: dose response and time course

Analysis of lungs of F344 females exposed to 0 to 200 ppm chloroprene (CR) for 5 or 15 days. CR, a monomer used in the production of neoprene elastomers, generates multiorgan tumors in mouse and rat cancer bioassays. Compared to mice (GDS4847), F344 rats are insensitive to CR-induced lung tumors.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 2 agent, 5 dose, 2 time sets

Platform:: GPL1355
Series:: GSE40795
50 Samples

Download data: CEL

DataSet

Accession:: GDS4848

ID:: 4848

Select item 1000013553.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...