GEO DataSets

(Submitter supplied) An efficient innate immune recognition of the intracellular parasite T. cruzi is crucial for host protection against development of Chagas disease, which often leads to multiple organ damage, particularly the heart leading to cardiomyopathy. Mechanisms modulated by MyD88 have been shown to be necessary for resistance against T, cruzi infection. Recently, Nod-like receptors have been shown to play an important role as innate immune sensors, particularly as they relate to inflammasome function, caspase activation, and inflammatory cytokine production. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5112

Platform:

GPL8321

6 Samples

Download data: CEL, CHP, XLS

Analysis of hearts of C57BL/6 animals infected with the intracellular parasite Trypanosoma cruzi. T. cruzi causes Chagas disease which can lead to cardiomyopathy. Results provide insight into the molecular mechanisms underlying the innate immune response in the heart to T. cruzi infections.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 infection sets

Platform:

GPL8321

Series:

GSE41089

6 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...

Organism:

Mus musculus

66 DataSets

523 Series

2 Related Platforms

6974 Samples

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