GEO DataSets

(Submitter supplied) β-cell identity is determined by tightly regulated transcriptional networks that are modulated by extracellular cues, thereby ensuring β-cell adaptation to the organism’s insulin demands. We have observed in pancreatic islets that stimulatory glucose concentrations induced a gene profile that was similar to that of freshly isolated islets, indicating that glucose-elicited cues are involved in maintaining β-cell identity. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS4939 GDS4942

Platform:

GPL1261

26 Samples

Download data: CEL

Analysis of islets isolated from young and aged animals and cultured for 2 days at 3 to 16mM glucose (G3 to G16). Freshly-isolated islets were also examined. Ageing is associated with functional changes in beta cells. Results provide insight into the molecular response of aged islets to glucose.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 age, 5 dose, 2 protocol sets

Platform:

GPL1261

Series:

GSE42591

20 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4546 Series

40 Related Platforms

58941 Samples

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