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Items: 4

1.

Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes

(Submitter supplied) We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene expression profiles of tumors that arose in irradiated mice are distinct from those that arose in naïve hosts. Host irradiation induces a metaprofile consisting of gene modules representing stem cells, cell motility, macrophages and autophagy. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Datasets:
GDS4768 GDS4769
Platform:
GPL1261
56 Samples
Download data: CEL
Series
Accession:
GSE42742
ID:
200042742
2.
Full record GDS4768

Radiation chimera model: Trp53-null mammary tumors arising from irradiated, wildtype hosts

Analysis of Trp53-null mammary tumors arising from WT hosts cleared of mammary gland epithelium, irradiated, then transplanted with nonmalignant Trp53-null mammary tissue. Results provide insight into the influence of the radiation response of the microenvironment on the carcinogenic process.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol sets
Platform:
GPL1261
Series:
GSE42742
32 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4547 Series
40 Related Platforms
58950 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

WT Sham-IR-host_17

Organism:
Mus musculus
Source name:
Total RNA of p53null mammary tumor, WT-Sham-irradiated host
Platform:
GPL1261
Series:
GSE42742
Dataset:
GDS4768
Download data: CEL
Sample
Accession:
GSM1049025
ID:
301049025
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