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Items: 4

1.

Stress-response pathways are altered in the hippocampus of chronic alcoholics.

(Submitter supplied) Comparison of gene expression in post-mortem hippocampus from 20 alcoholics and 19 controls. The chronic high-level alcohol consumption seen in alcoholism leads to dramatic effects on the hippocampus, including decreased white matter, loss of oligodendrocytes and other glial cells, and inhibition of neurogenesis. Examining gene expression in post mortem hippocampal tissue from 20 alcoholics and 19 controls allowed us to detect differentially expressed genes that may play a role in the risk for alcoholism or whose expression is modified by chronic consumption of alcohol. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4879
Platform:
GPL6244
39 Samples
Download data: CEL
Series
Accession:
GSE44456
ID:
200044456
2.
Full record GDS4879

Chronic high-level alcohol consumption effect on brain: post-mortem hippocampus

Analysis of post-mortem hippocampus of chronic alcoholics (CAs). Chronic high-level alcohol consumption leads to decreased white matter and inhibition of neurogenesis. Results provide insight into molecular mechanisms that may play a role in the risk for alcoholism.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 2 gender sets
Platform:
GPL6244
Series:
GSE44456
39 Samples
Download data: CEL
3.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Homo sapiens
136 DataSets
1879 Series
27 Related Platforms
38399 Samples
Download data
Platform
Accession:
GPL6244
ID:
100006244
4.

male_alcoholic_108

Organism:
Homo sapiens
Source name:
male_alcoholic
Platform:
GPL6244
Series:
GSE44456
Dataset:
GDS4879
Download data: CEL
Sample
Accession:
GSM1085671
ID:
301085671
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