GSM1091959[Accession] - GEO DataSets

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Items: 3

Select item 2000448051.

Capturing the biological impact of the melanoma susceptibility genes CDKN2A and MC1R in cocultured keratinocytes and melanocytes

(Submitter supplied) Germline mutations in CDKN2A and/or red hair colour variants in MC1R genes are associated with an increased susceptibility to develop cutaneous melanoma. To investigate the impact of germinal p.G101W CDKN2A mutation and MC1R variants on gene expression and transcription profiles associated to skin cancer and melanoma in particular, we set-up primary skin cultures from twins belonging to the melanoma prone-families with and without these genomic features. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6480
12 Samples

Download data: TXT

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Accession:: GSE44805

ID:: 200044805

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000064802.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...