GEO DataSets

(Submitter supplied) Quetiapine is an atypical neuroleptic with a pharmacological profile distinct from classic neuroleptics. It is currently approved for treating patients with schizophrenia, major depression and bipolar I disorder. However, its cellular effects remain elusive. We used microarrays to characterize RNA transcript levels in the brains of mice chronically treated with quetiapine, the neuroleptic haloperidol, or vehicle. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4623

Platform:

GPL1261

20 Samples

Download data: CEL

Analysis of frontal cortex and striatum from males treated with quetiapine at doses of 10 or 100 mg/kg, twice a day for 28 days. Quetiapine has pharmacological actions distinct from classic neuroleptics. Results provide insight into molecular basis of the unique therapeutic profile of quetiapine.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 3 agent, 5 dose, 2 tissue sets

Platform:

GPL1261

Series:

GSE45229

20 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4546 Series

40 Related Platforms

58941 Samples

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