GSM1120066[Accession] - GEO DataSets

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Items: 4

Select item 2000459411.

Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice

(Submitter supplied) Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor Tcfap2c / TFAP2C has been described to be essential for primordial germ cell maintenance and to be upregulated in several human germ cell cancers. Using global gene expression profiling, we identified genes deregulated upon loss of Tcfap2c in primordial germ cell-like cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5382
Platform:: GPL1261
8 Samples

Download data: CEL

Series

Accession:: GSE45941

ID:: 200045941

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53822.

Transcription factor Tcfap2c deficiency effect on primordial germ cells

Analysis of embryonic stem cells (ESCs) depleted for transcription factor Tcfap2c and PGC-like cells (PGCLCs) derived from the Tcfap2c-deficient ESCs. TFAP2C is a member of the activator protein-2 (AP-2) family. Results provide insight into the role of TFAP2C in germ cell fate.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 cell type, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE45941
8 Samples

Download data: CEL

DataSet

Accession:: GDS5382

ID:: 5382

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...