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Items: 4

1.

Expression data from responders/nonresponders before/after receiving DLI for relapse of CML s/p BMT

(Submitter supplied) Increasing evidence across malignancies suggests that infiltrating T cells at the site of disease are crucial to tumor control. We hypothesized that marrow-infiltrating immune populations play a critical role in response to donor lymphocyte infusion (DLI), an established and potentially curative immune therapy whose precise mechanism remains unknown. We therefore analyzed marrow-infiltrating immune populations in 29 patients (22 responders, 7 nonresponders) with relapsed chronic myelogenous leukemia who received CD4+ DLI in the pre-tyrosine kinase inhibitor era. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4871
Platform:
GPL571
12 Samples
Download data: CEL
Series
Accession:
GSE49067
ID:
200049067
2.
Full record GDS4871

Donor lymphocyte infusion effect on bone marrow-infiltrating CD3+ T cells of patients with relapsed chronic myelogenous leukemia

Analysis of marrow-infiltrating CD3+ T cells isolated from relapsed chronic myelogenous leukemia (CML) patients following donor lymphocyte infusion (DLI) therapy. Four patients were DLI-responsive, two were DLI-nonresponsive. Results provide mechanistic insights into DLI response in relapsed CML.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 individual, 2 protocol sets
Platform:
GPL571
Series:
GSE49067
12 Samples
Download data: CEL
3.

[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Human Genome U133A 2.0 Array is a single array representing 14,500 well-characterized human genes that can be used to explore human biology and disease processes. more...
Organism:
Homo sapiens
84 DataSets
641 Series
12 Related Platforms
24467 Samples
Download data
Platform
Accession:
GPL571
ID:
100000571
4.

marrow CD3 T cells_pre_R3 (responder)

Organism:
Homo sapiens
Source name:
marrow derived CD3+ T cells, before DLI
Platform:
GPL571
Series:
GSE49067
Dataset:
GDS4871
Download data: CEL
Sample
Accession:
GSM1193266
ID:
301193266
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