GSM122986[Accession] - GEO DataSets

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Items: 3

Select item 2000053811.

Gene expression analysis of liver and kidney following methapyrilene treatment in male Sprague-Dawley rats

(Submitter supplied) This study was performed to gain insight into the hepatotoxicity of methapyrilene. Gene expression changes in the kidney (non-target tissue for toxicity) were compared to those in the liver (target tissue for toxicity) to attribute gene expression changes to relevant biological processes (i.e. toxic response, non-specific acute response, pharmacological response, etc…). Keywords: Time course, tissue comparison, liver toxicity, hepatotoxicity

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL890
48 Samples

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Accession:: GSE5381

ID:: 200005381

Analyze with GEO2R

Select item 1000008902.

Agilent-011868 Rat Oligo Microarray G4130A (Feature Number version)

(Submitter supplied) This microarray contains representative sequences derived from rat RefSeq, high-quality public rat mRNA accessions, homologs to human and mouse RefSeq, EST clusters determined by a leading biopharmaceutical company and the Incyte Zooseq database as well as toxicology markers determined by the National Institute of Environmental Health Sciences (NIEHS) and others. Many of the toxicology markers used in the design of this microarray were released to the public domain for the first time and will be used on this unique microarray product. more...