GEO DataSets

(Submitter supplied) Our main objective was to study genome-wide differential methylation in de novo glioblastoma multiforme (GBM, grade IV glioma). We evaluated CpG sites in gene promoters of 26,000+ genes using an array-based chip. We retrieved 54 GBM from biorepositories of two institutions(40 from Columbia University and 14 from Case Western Reserve University) and 24 control brain tissues from the New York Brain Bank, which collected control brain tissues from consented subjects without history of neurological diseases at autopsy.

Organism:

Homo sapiens

Type:

Methylation profiling by array

Platform:

GPL8490

78 Samples

Download data: TXT

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...

Organism:

Homo sapiens

348 Series

19058 Samples

Download data: CSV