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Items: 4

1.

Interleukin-6 is a Potential Therapeutic Target in Interleukin-6 Dependent Estrogen Receptor-alpha Positive Breast Cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL18189 GPL18190
371 Samples
Download data: CEL
Series
Accession:
GSE54331
ID:
200054331

Analyze with GEO2R

2.

Interleukin-6 is a Potential Therapeutic Target in Interleukin-6 Dependent Estrogen Receptor-alpha Positive Breast Cancer [cell lines]

(Submitter supplied) Interleukin-6 (IL-6) is an important growth factor for estrogen receptor-alpha (ERα) positive breast cancer, and elevated serum IL-6 is associated with poor prognosis. We firstly demonstrated that pSTAT3 is the primary downstream IL-6 signaling pathway in ERα-positive breast cancer, using ten different breast cancer cell lines. Three-dimensional cultures of these cell lines were also used to develop a 17-gene IL-6 specific gene signature that could be used to identify IL-6 driven disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL18189
335 Samples
Download data: CEL
Series
Accession:
GSE54329
ID:
200054329

Analyze with GEO2R

3.

[HG-U219] Affymetrix Human Genome U219 Array [CDF: Brainarray HGU219_Hs_ENTREZG_15.1.0]

(Submitter supplied) This identical to GPL13667 but a custom cdf environmnet was used to extract data. Protocol: see manufacturer's website
Organism:
Homo sapiens
3 Series
1 Related Platform
405 Samples
Download data: CDF, TXT
Platform
Accession:
GPL18189
ID:
100018189

4.

BT-483 treated with 10 ng/mL IL-6 d0 + 50 ug Siltuximab d1, day 4_rep3

Organism:
Homo sapiens
Source name:
BT-483_10 ng/mL IL-6 d0 + 50 ug Siltuximab d1_day 4
Platform:
GPL18189
Series:
GSE54329 GSE54331
Download data: CEL
Sample
Accession:
GSM1313129
ID:
301313129

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