GSM1314044[Accession] - GEO DataSets

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Items: 4

Select item 2000543721.

Heart tissue from Nelf-b CreER mice

(Submitter supplied) Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains unclear. Here we show for the first time that whole-body conditional deletion of the B subunit of NELF (NELF-B) in adult mice results in cardiomyopathy and impaired response to cardiac stress. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5302
Platform:: GPL6885
6 Samples

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Series

Accession:: GSE54372

ID:: 200054372

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 53022.

Negative elongation factor B subunit deficiency effect on the heart

Analysis of heart left ventricles from mutants lacking the B subunit of negative elongation factor (NELF). NELF is a regulator of RNA polymerase II pausing. Results provide insight into the role of NELF in myocardial function.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 genotype/variation sets

Platform:: GPL6885
Series:: GSE54372
6 Samples

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DataSet

Accession:: GDS5302

ID:: 5302

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000068853.

Illumina MouseRef-8 v2.0 expression beadchip

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...