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Items: 3

1.

Non-clonal mosaicism in human somatic and embryonic stem cells revealed by single-cell array-based copy-number variation analysis

(Submitter supplied) Although it is known that cultured human cells acquire copy number variations over time, little is known about the mutation frequency in individual cells. Here we describe that human somatic and embryonic stem cell cultures show significant fractions of cells carrying unique chromosomal abnormalities, forming a non-clonal genetic mosaic. We studied 85 human single cells by array-based comparative genomic hybridisation and found that 14-31% of hESC and 8-26% of somatic cells are chromosomally abnormal. more...
Organism:
Homo sapiens
Type:
Genome variation profiling by genome tiling array
Platform:
GPL17760
106 Samples
Download data: TXT
Series
Accession:
GSE51126
ID:
200051126
2.

BlueGnome/Illumina 24sure v3.0

(Submitter supplied) BAC array-based comparative genomic hybridization Protocol: http://www.cambridgebluegnome.com/products/24sure
Organism:
Homo sapiens
8 Series
392 Samples
Download data
Platform
Accession:
GPL17760
ID:
100017760
3.

VUB07 P165BBB7 pooled

Organism:
Homo sapiens
Source name:
hESC culture (channel 1) female/male reference (channel 2)
Platform:
GPL17760
Series:
GSE51126
Download data: TXT
Sample
Accession:
GSM1334885
ID:
301334885
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db=gds|term=GSM1334885[Accession]|query=1|qty=2|blobid=MCID_6770d0267eb86f557f6b72b7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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