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Items: 3

1.

Histone chaperone HIRA orchestrates H4K16ac-decorated dynamic chromatin in senescent cells and is required for suppression of oncogene-induced neoplasia.

(Submitter supplied) Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Histone chaperone HIRA deposits nucleosome-destabilizing histone variant H3.3 into chromatin in a DNA replication-independent manner. Histone H3.3 and a subset of other typically “replication-dependent” core histones were expressed in non-proliferating senescent cells, the latter linked to alternative mRNA splicing and polyadenylation. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL10999
22 Samples
Download data: BED, BIGWIG, CSV
Series
Accession:
GSE56307
ID:
200056307

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina Genome Analyzer IIx (Homo sapiens)

Organism:
Homo sapiens
1102 Series
10066 Samples
Download data
Platform
Accession:
GPL10999
ID:
100010999

3.

HIRA RS input DNA

Organism:
Homo sapiens
Source name:
Fibroblasts
Platform:
GPL10999
Series:
GSE56307
Download data: BIGWIG
Sample
Accession:
GSM1358816
ID:
301358816

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db=gds|term=GSM1358816[Accession]|query=1|qty=2|blobid=MCID_675971fbc087e36732a78aa9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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