GEO DataSets

(Submitter supplied) Uncontrolled Transforming growth factor-beta (TGFβ) signaling promotes aggressive metastatic properties in late-stage breast cancers. However, how TGFβ-mediated cues are directed to induce late-stage tumorigenic events is poorly understood, particularly given that TGFβ has clear tumor suppressing activity in other contexts. Here we demonstrate that the transcriptional regulators TAZ and YAP (TAZ/YAP), key effectors of the Hippo pathway, are necessary to promote and maintain TGFβ-induced tumorigenic phenotypes in breast cancer cells. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL15034

12 Samples

Download data: CEL

(Submitter supplied) custom CDF: HuGene10stv1_Hs_ENTREZG.cdf [Brainarray Version 14] Protocol: See manufacturer's web site

Organism:

Homo sapiens

16 Series

1 Related Platform

230 Samples

Download data: CDF, TXT