GSM143129[Accession] - GEO DataSets

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Items: 4

Select item 2000061191.

Exogenous Glucosamine Globally Protects Chondrocytes from the Arthritogenic Effects of IL-1beta

(Submitter supplied) Glucosamine proved to be a potent, broad-spectrum inhibitor of IL-1beta. Of the 2,813 genes whose transcription was altered by IL-1beta stimulation (p<0.0001), glucosamine significantly blocked the response in 2,055 (~73%). Glucosamine fully protected the chondrocytes from IL-1-induced expression of inflammatory cytokines, chemokines and growth factors as well as proteins involved in PGE2 and NO synthesis. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS2472
Platform:: GPL1355
13 Samples

Download data: CEL

Series

Accession:: GSE6119

ID:: 200006119

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 24722.

Glucosamine and interleukin-1 beta effect on chondrocytes

Analysis of cultured articular chondrocytes treated with glucosamine for 6 hours and then by interleukin-1 beta for 14 hours. Cytokines, such as interleukin-1 (IL-1), contribute to the pathogenesis of osteoarthritis. Results provide insight into the anti-arthritic properties of glucosamine.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, count, 4 agent sets

Platform:: GPL1355
Series:: GSE6119
13 Samples

Download data: CEL

DataSet

Accession:: GDS2472

ID:: 2472

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000013553.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...