GSM1500677[Accession] - GEO DataSets

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Items: 3

Select item 2000612421.

Epigenetic assimilation in the aging human brain

(Submitter supplied) Epigenetic drift progressively increases variation in DNA modification profiles of aging cells, but the finale of such divergence remains elusive. In this study, we explored the dynamics of DNA modification and transcription in the later stages of human life. We find that brain tissues of older individuals (>75 years) become more similar to each other, both epigenetically and transcriptionally, compared with younger individuals. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL2040
76 Samples

Download data: GPR

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Accession:: GSE61242

ID:: 200061242

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000020402.

UHN Human CpG 12K Array (HCGI12K)

(Submitter supplied) This array contains single-spotted clones representing 12,192 CpG-island clones from the Sanger Institute. The CpG Library was originally prepared by Sally Cross in the laboratory of Adrian Bird at The Wellcome Trust Centre for Cell Biology (University of Edinburgh). For information on the preparation of the original library, please see Cross, S.H., et.al., Purification of CpG islands using a methylated DNA binding column. more...