GEO DataSets

(Submitter supplied) Exposure to air particulate matter is associated with increased cardiovascular morbidity and mortality. One of the possible mechanisms is by promotion of atherosclerosis mediated by synergy of particulate matter chemicals and oxidized phospholipids on vascular endothelial cells. We treated human microvascular endothelial cells (HMEC) in triplicate wells with diesel exhaust particles (DEP) extract at a concentration of 5 and 25 mcg/ml, oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphorylcholine (ox-PAPC) at concentrations of 10, 20 and 40 mcg/ml or combination of DEP at 5 mcg/ml plus ox-PAPC at 10, 20 and 40 mcg/ml. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2889

Platform:

GPL2700

27 Samples

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Analysis of microvascular endothelial cells treated at various concentrations of the model air pollutant diesel exhaust particles (DEP), an oxidized phospholipid (ox-PAPC), or both. Results provide insight into the synergistic effect of DEP and ox-PAPC in promoting vascular inflammation.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 4 agent, 9 dose sets

Platform:

GPL2700

Series:

GSE6584

27 Samples

Download data: TXT

(Submitter supplied) The Sentrix® HumanRef-8 BeadChip can be used to study expression of over 23,000 human transcripts from the NCBI RefSeq database. Researchers can generate whole-genome expression profiles for 8 samples in parallel on a single BeadChip. The array is composed of 3 micron features with average feature redundancy of 30-fold. All features are quality controlled by sequential hybridizations process called array decoding. more...

Organism:

Homo sapiens

8 DataSets

38 Series

1586 Samples

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