GSM172908[Accession] - GEO DataSets

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Items: 4

Select item 2000071871.

Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for DMD

(Submitter supplied) Duchenne Muscular Dystrophy (DMD) is a fatal muscle wasting disorder caused by dystrophin deficiency. Previous work suggested that increased expression of the dystrophin-related protein utrophin in the mdx mouse model of DMD can prevent dystrophic pathophysiology. Physiological tests showed that the transgenic mouse muscle functioned in a way similar to normal muscle. More recently, it has become possible to analyse disease pathways using microarrays, a sensitive method to evaluate the efficacy of a therapeutic approach. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3398
Platform:: GPL339
17 Samples

Download data: CEL

Series

Accession:: GSE7187

ID:: 200007187

Select item 33982.

Utrophin overexpression effect on dystrophin-deficient mdx skeletal muscles

Analysis of skeletal muscles from dystrophin-deficient mdx trangenics engineered to overexpress utrophin, a dystrophin-related protein. Dystrophin mutations result in Duchenne muscular dystrophy. mdx trangenics overexpressing utrophin display improved muscle function.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 3 strain sets

Platform:: GPL339
Series:: GSE7187
17 Samples

Download data: CEL

DataSet

Accession:: GDS3398

ID:: 3398

Select item 1000003393.

[MOE430A] Affymetrix Mouse Expression 430A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321. June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...