GSM180042[Accession] - GEO DataSets

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Items: 4

Select item 2000074361.

Profiling of genes regulated by TGF-beta in lung carcinoma (A549) and immortalized lung epithelial (HPL1D)cells.

(Submitter supplied) TGF-beta is one of the key cytokines implicated in various disease processes including cancer. TGF-beta inhibits growth and promotes apoptosis in normal epithelial cells and in contrast, acts as a pro-tumour cytokine by promoting tumour angiogenesis, immune-escape and metastasis. It is not clear if various actions of TGF-beta on normal and tumour cells are due to differential gene regulations. Hence we studied the regulation of gene expression by TGF-beta in normal and cancer cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2932
Platform:: GPL3515
12 Samples

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Accession:: GSE7436

ID:: 200007436

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 29322.

TGF-beta effect on normal and tumor cell lines: time course

Analysis of normal lung epithelial HPL1D cells and lung adenocarcinoma A549 cells treated with TGF-beta for up to 12 hours. TGF-beta inhibits growth and promotes apoptosis in normal epithelial cells but acts as a pro-tumor cytokine by promoting tumour angiogenesis, immune-escape, and metastasis.

Organism:: Homo sapiens

Type:: Expression profiling by array, log2 ratio, 2 cell line, 3 time sets

Platform:: GPL3515
Series:: GSE7436
12 Samples

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DataSet

Accession:: GDS2932

ID:: 2932

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000035153.

UHN-Toronto 19K single spotted Human EST microarray v7

(Submitter supplied) Microarrays are printed on UltraGAPS™ slides (Corning Inc.) using high-precision robotics. Printed arrays are processed following Corning's protocol and are ready-to-use. Single-spotted array containing 19,008 characterized and unknown human ESTs. The clone set has been sequence-verified at the Microarray Centre After printing, the slides are subjected to processing and performance testing based on true labelling, hybridization and scanning procedures. more...