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Items: 3

1.

FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function

(Submitter supplied) FOXA1 is a FKHD family protein that translates epigenetic signatures at target enhancers to lineage-specific transcription and differentiation. Through genome-wide location analyses, here we show that FOXA1 expression and occupancy are, in turn, required for the maintenance of this epigenetic signature, namely DNA hypomethylation and histone 3 lysine 4 methylation. Mechanistically, this involves TET1, a 5-methylcytosine dioxygenase. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL15456
18 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE73363
ID:
200073363
2.

Illumina HiScanSQ (Homo sapiens)

Platform
Accession:
GPL15456
ID:
100015456
3.

PC-3M, TAmC-seq

Organism:
Homo sapiens
Source name:
prostate cell line
Platform:
GPL15456
Series:
GSE73363
Download data: BEDGRAPH, TXT
Sample
Accession:
GSM1891821
ID:
301891821
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