GEO DataSets

(Submitter supplied) Non-coding microRNAs (miRNAs) mainly regulate the expression of targeted genes by regulating mRNA degradation or repressing their protein translation. MiRNA microarray profiling was then performed on 218 human HCC tumors samples, 10 samples from adjacent cirrhotic non-tumoral tissue, 10 samples from healthy liver and 12 HCC cell lines. In this study we investigated which miRNAs were differentially expressed in HCC compared to cirrhotic non-tumoral tissue and healthy liver.

Organism:

synthetic construct; Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL14613

250 Samples

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(Submitter supplied) #%create_date=Wed Dec 22 13:03:44 PST 2010 #%guid=04795ed5-9038-4dff-957e-da346791f552 #%chip_type=miRNA-2_0 # File order is all miRNAs that have mapping information grouped by organism, then all miRNAs without mapping information grouped by organism, then all sno/sca from UCSC and ensembl, and lastly the controls. # miRNAs: # An annot name generally represents one genome location," but may refer to multiple annotations because of multiple mature products delineated by ""-3p"" and ""-5p"""," or "".1"" and "".2""." # Also, those with a '*' are minor products, and those without '*' or any other aforementioned suffix are considered the major product. more...

Organism:

synthetic construct

187 Series

3459 Samples

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