GSM1937427[Accession] - GEO DataSets

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Items: 4

Select item 2000753841.

Lineage-specific and single cell chromatin accessibility charts human hematopoiesis and leukemia evolution

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL18573 GPL11154 GPL16791
787 Samples

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Accession:: GSE75384

ID:: 200075384

Select item 2000749122.

ATAC-seq data

(Submitter supplied) A single hematopoietic stem cell can give rise to all blood cells with remarkable fidelity. Here, we define the chromatin accessibility and transcriptional landscape controlling this process in thirteen primary cell types that traverse the hematopoietic hierarchy. Exploiting the finding that enhancer landscapes better reflect cell identity than mRNA levels, we enable "enhancer cytometry" for accurate enumeration of pure cell types from complex populations. more...