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Items: 3

1.

Genomic instability induced by lowered expression of POL3 in yeast

(Submitter supplied) DNA replication stress (DRS)-linked genomic instability has emerged as an important factor driving cancer development. To understand the mechanisms of DRS-associated genomic instability and phenotypic evolution, we mapped chromosomal alterations in a yeast strain with lowered expression of the replicative DNA polymerase δ. At a whole-genome level, we identified both hotspots of mitotic recombination and chromosome-specific aneuploidy dependent on decreased levels of DNA polymerase δ. more...
Organism:
Saccharomyces cerevisiae
Type:
Genome variation profiling by genome tiling array; Genome variation profiling by SNP array
Platforms:
GPL21552 GPL21553 GPL20144
109 Samples
Download data: GPR, TXT
Series
Accession:
GSE78856
ID:
200078856
2.

Agilent-027438 Yeast S-Y SNP v1 [Probe Name Version]

(Submitter supplied) Whole genome SNPs between S288c and YJM789. Both Watson and Crick strands represented as well as both probes specific to both strains. In the labels of the oligonucleotides 'SF', 'SR', 'YF' and 'YR' refer to the orientation and origin of the sequences used for the oligonucleotides on the microarrays. 'S' and 'Y' indicate whether the oligonucleotide contains sequences identical to the reference S288c genome (closely related to W303-1A) or the YJM789 genome, respectively. more...
Organism:
Saccharomyces cerevisiae
13 Series
1 Related Platform
367 Samples
Download data
Platform
Accession:
GPL20144
ID:
100020144
3.

DZ12_lowgal_34 (DZ12-34)

Organism:
Saccharomyces cerevisiae
Source name:
DZ12-derived isolates (channel 1) Control strain JSC24 (channel 2)
Platform:
GPL20144
Series:
GSE78856
Download data: GPR, TXT
Sample
Accession:
GSM2079658
ID:
302079658
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