GEO DataSets

(Submitter supplied) Time-course gene expression profiles were obtained from lung tissues of the rats treated with room air, intermittent- (IH) or sustained hypoxia (SH) for 1, 3, 7, 14 and 30 days using CodeLink microarrays. Using a systems biology approach, we observed that two different mechanisms are involved in the lung responses to IH and SH: IH leads to increased G-protein coupled signaling-, ion transport-, neuronal- and steroid hormone receptor activities; whereas SH causes increased blood vessel morphogenesis and immune responses. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3914

Platform:

GPL2890

42 Samples

Download data: TXT

Analysis of lungs from adult males subjected to intermittent (IH) or sustained hypoxia (SH) for up to 30 days. IH is associated with sleep-disordered breathing, and SH with parenchymal lung disorders. Results provide insight into molecular mechanisms underlying hypoxic lung response during IH or SH.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, transformed count, 3 stress, 6 time sets

Platform:

GPL2890

Series:

GSE8705

42 Samples

Download data: TXT

(Submitter supplied) CodeLink UniSet Rat I is designed for expression monitoring of a broad range of rat genes derived from NCBI and clustered to generate consensus sequences. Identifying patterns of differential mRNA expression over a large set of genes is an excellent method to identify targets, characterize action mechanisms, and make initial predictions of global drug effects. Well-annotated mRNA or coding sequences were chosen from the entire UniGene set to ensure usefulness to a large range of researchers in basic research, biotechnology, and drug development applications. more...

Organism:

Rattus norvegicus

1 DataSet

5 Series

140 Samples

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