GEO DataSets

(Submitter supplied) In response to acute infection, naive CD8+ T cells expand, differentiate into effector cells and then contract to a long-lived pool of memory cells after pathogen clearance. During chronic infections or in tumors, CD8+ T cells acquire an “exhausted” phenotype. Here we present genome-wide comparisons of chromatin accessibility and gene expression from endogenous CD8+ T cells responding to acute and chronic viral infection using ATAC-seq and RNA-seq. more...

Organism:

Mus musculus

Type:

Other; Expression profiling by high throughput sequencing

Platform:

GPL17021

44 Samples

Download data: TSV