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Items: 4

1.

A transcriptional repressor and co-repressor induced by the STAT3-regulated anti-inflammatory signaling pathway.

(Submitter supplied) IL-10 regulates anti-inflammatory signaling via the activation of STAT3, which in turn controls the induction of a gene expression program whose products execute inhibitory effects on pro-inflammatory mediator production. Here we show that IL-10 induces the expression of an ETS family transcriptional repressor, ETV3 and a helicase family co-repressor, SBNO2 (Strawberry notch homolog 2) in mouse and human macrophages. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3190
Platform:
GPL1261
18 Samples
Download data: CEL
Series
Accession:
GSE9509
ID:
200009509
2.
Full record GDS3190

Macrophage response to lipopolysaccharide and interleukin-10 co-treatment: time course

Analysis of interleukin-10 (IL-10)-deficient macrophages at various time points up to 30 minutes following co-stimulation with lipopolysaccharide (LPS) and IL-10. LPS elicits an inflammatory response. Results provide insight into molecular mechanisms underlying the anti-inflammatory effect of IL-10.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 3 time sets
Platform:
GPL1261
Series:
GSE9509
18 Samples
Download data: CEL
DataSet
Accession:
GDS3190
ID:
3190
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4546 Series
40 Related Platforms
58941 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

LPS plus IL-10, 30 min, Rep_1

Organism:
Mus musculus
Source name:
IL-10 -/- bone marrow derived macrophages treated with LPS (100 ng/ml) plus IL-10 (10 ng/ml) for 30 minutes
Platform:
GPL1261
Series:
GSE9509
Dataset:
GDS3190
Download data: CEL
Sample
Accession:
GSM241143
ID:
300241143
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