GEO DataSets

(Submitter supplied) Chromosome segregation in mitosis and meiosis depends on sister chromatid cohesion mediated by cohesin complexes. Mutation of cohesin and other cohesion proteins causes transcriptional and developmental defects in animals and humans, but the molecular cause of these phenotypes is unknown. Here we describe 8811 cohesin binding sites in the human genome and show that the CCCTC-binding factor (CTCF) is associated with 88% of these. more...

Organism:

Homo sapiens

Type:

Expression profiling by array; Genome binding/occupancy profiling by genome tiling array

17 related Platforms

50 Samples

Download data: CEL

(Submitter supplied) For data analysis of the associated Samples, we calculated MAT scores based on the hyridization intensity data of the probes within 500bp windows. The coordinate column in the Platform data table represents the chromosome coordinates for the 500bp window center positions. The supplementary files (linked below) also report the 500bp window start and end positions (and also sequence of 500bp unit region for used for analysis). more...

Organism:

Homo sapiens

1 Series

11 Samples

Download data: TXT