GEO DataSets

(Submitter supplied) To identify molecular changes underlying the chemopreventive or tumor promoting effects of SRD5A inhibition, we profiled gene expression changes in benign prostate epithelium from patients with PCa treated with dutasteride, a dual SRD5A inhibitor. Subjects were aged 45-80 years with clinically localized PCa (T1C to T2b), Gleason score <7, and serum PSA 2.5-10 ng/dL. 81 men were randomized to immediate RP (n=25) or to dutasterdie at 0.5 mg (n=26) or 3.5 mg (n=24) orally per day for four months prior to RP. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL4768

40 Samples

Download data: GPR

(Submitter supplied) FHCRC Human Prostate PEDB cDNA Array v10 Protocol: DNA spotted onto polylysine-coated glass microscope slides

Organism:

Homo sapiens

3 Series

53 Samples

Download data