GSM252927[Accession] - GEO DataSets

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Items: 3

Select item 2000100091.

Cooperative Signaling Through the STAT3 and NF-kB Pathways in Subtypes of DLBCL

(Submitter supplied) The activated B cell-like (ABC) subgroup of diffuse large B cell lymphoma (DLBCL) is characterized by constitutive activation of the NF-êB pathway. Here we show that the NF- êB pathway induces the expression of the cytokines IL-6 and IL-10 in ABC DLBCL cell lines, which also have high levels of total and phosphorylated STAT3 protein, suggesting autocrine signaling. Using RNA interference for STAT3, we defined a gene expression signature of IL-6 and IL-10 signaling through STAT3. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL3278
40 Samples

Download data: GPR

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Accession:: GSE10009

ID:: 200010009

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000032782.

NCI/Staudt human 15K v13

(Submitter supplied) See reference Alizadeh et al. The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harb Symp Quant Biol. 64, 71-8 (1999).