GSM2629610[Accession] - GEO DataSets

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Items: 4

Select item 2000989851.

Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
12 Samples

Download data: BW

Series

Accession:: GSE98985

ID:: 200098985

PubMed Similar studies

Select item 2000989832.

Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [ChIP-seq]

(Submitter supplied) Over activation of NF-κB has close relationship with hepatitis and hepatocellular carcinoma (HCC). In this study, by manipulating NF-κB activity with its recognized activator TNFα and using ChIP-seq and RNA-seq techniques, we identified 699 NF-κB direct target genes (DTGs) in a widely used HCC cell line, HepG2, including 399 activated and 300 repressed genes. In these NF-κB DTGs, 216 genes (126 activated and 90 repressed genes) are among the current HCC gene signature. more...