GEO DataSets

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS905

Platform:

GPL341

25 Samples

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Analysis of gene expression in pancreatic beta cell line INS-1 overexpressing the transcription factors HNF1b, HNF4a2, HNF6, or mutant forms of HNF1b, which were introduced by FRT/FLP recombination. Dysfunction of these transcription factors cause maturity onset diabetes of the young (MODY).

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 5 cell line, 3 genotype/variation, 2 protocol sets

Platform:

GPL341

Series:

GSE6428

25 Samples

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(Submitter supplied) A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors HNF1b and HNF1b mutants were identified. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL341

12 Samples

Download data

(Submitter supplied) A rat insulinoma cell line (INS-1) was generated that contains a FRT site for FLP recombinase mediated site specific integration of specific genes. In addition, the line contains the tetracycline repressor allowing tetracycline (tet) induction of the introduced gene. By comparing the gene expression profiles of uninduced and tet-induced cells, target genes of introduced transcription factors HNF1b, HNF4a2, and HNF6 (onecut1) were identified. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL341

12 Samples

Download data

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Array A of GeneChip Rat Expression Set 230 Has 15923 entries and was indexed 09-Apr-2003 Sequences used in the design of the array were selected from GenBank, dbEST, and RefSeq. more...

Organism:

Rattus norvegicus

68 DataSets

148 Series

2 Related Platforms

3292 Samples

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