GSM2722474[Accession] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 3

Select item 2001020541.

FFK506-Binding Protein 12.6/1b, a negative regulator of [Ca2+], rescues memory and restores genomic regulation in the hippocampus of aging rats

(Submitter supplied) Hippocampal overexpression of FK506-binding protein 12.6/1b (FKBP1b), a negative regulator of ryanodine receptor Ca2+ release, reverses aging-induced memory impairment and neuronal Ca2+ dysregulation. Here, we test the hypothesis that FKBP1b also can protect downstream transcriptional networks from aging-induced dysregulation. We gave hippocampal microinjections of FKBP1b-expressing viral vector to male rats at either 13-months-of-age (long-term) or 19-months-of-age (short-term) and tested memory performance in the Morris water maze at 21-months-of-age. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL6247
23 Samples

Download data: CEL

Series

Accession:: GSE102054

ID:: 200102054

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000062472.

[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html #%create_date=Wed Mar 11 16:20:04 2009 PDT #%chip_type=RaGene-1_0-st-v1 #%lib_set_name=RaGene-1_0-st #%lib_set_version=v1 #%genome-species=Rattus norvegicus #%genome-version=rn4 #%genome-version-ucsc=rn4 #%genome-version-ncbi=HGSC v3.4 #%genome-version-create_date=2004-11 #%netaffx-annotation-date=2009-03-16 #%netaffx-annotation-netaffx-build=28 Protocol: See manufacturer's web site