GSM2806184[Accession] - GEO DataSets

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Items: 4

Select item 2001047051.

Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL18573
92 Samples

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Accession:: GSE104705

ID:: 200104705

PubMed Full text in PMC Similar studies

Select item 2000846182.

Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease [ChIP-Seq]

(Submitter supplied) Aging is the strongest risk factor for Alzheimer's disease (AD), although the underlying mechanisms remain unclear. The chromatin state, in particular through the mark H4K16ac, has been implicated in aging and thus may play a pivotal role in age-associated neurodegeneration. Here we compared the genome-wide enrichment of H4K16ac in the lateral temporal lobe of AD individuals against both younger and elderly cognitively normal controls. more...