GSM2809572[Accession] - GEO DataSets

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Items: 4

Select item 2001043341.

Cohesin loss eliminates all loop domains

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL20795 GPL16791 GPL18573
132 Samples

Download data: BW, HIC, TDF

Series

Accession:: GSE104334

ID:: 200104334

PubMed Full text in PMC Similar studies

Select item 2001043332.

Cohesin loss eliminates all loop domains [HiC]

(Submitter supplied) The human genome folds to create thousands of intervals, called “contact domains,” that exhibit enhanced contact frequency within themselves. “Loop domains” form because of tethering between two loci – almost always bound by CTCF and cohesin – lying on the same chromosome. “Compartment domains” form when genomic intervals with similar histone marks co-segregate. Here, we explore the effects of degrading cohesin. more...