GSM2892836[Accession] - GEO DataSets

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Items: 4

Select item 2001082301.

Single-cell transcriptome analysis of avian neural crest migration reveals signatures of invasion and molecular transitions

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Gallus gallus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19005
513 Samples

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Accession:: GSE108230

ID:: 200108230

PubMed Full text in PMC Similar studies

Select item 2001082212.

Single-cell transcriptome analysis of avian neural crest migration reveals signatures of invasion and molecular transitions [scRNA-seq]

(Submitter supplied) Neural crest cells migrate throughout the embryo, but how cells move in a directed and collective manner has remained unclear. Here, we perform the first single-cell transcriptome analysis of cranial neural crest cell migration at three progressive stages in chick and identify and establish hierarchical relationships between cell position and time-specific transcriptional signatures. We determine a novel transcriptional signature of the most invasive neural crest Trailblazer cells that is consistent during migration and enriched for approximately 900 genes. more...