GSM2976210[Accession] - GEO DataSets

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Items: 4

Select item 2001100041.

Repression of Divergent Noncoding Transcription by a Sequence-Specific Transcription Factor

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Other; Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL21656 GPL17342
49 Samples

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Series

Accession:: GSE110004

ID:: 200110004

PubMed Full text in PMC Similar studies

Select item 2001100032.

Identification of non-coding transcripts regulated by Rap1 and other transcription factors by RNA-seq analysis

(Submitter supplied) Eukaryotic cells utilize several mechanisms to ensure that expression of aberrant non-coding RNAs is limited. Gene looping, chromatin modification or remodeling, and RNA surveillance contribute to ensure the fidelity of transcription and limit non-coding transcripts. Here we identify that in Saccharomyces cerevisiae, the transcription factor Rap1 is critical for limiting the expression of aberrant RNAs, particularly near the highly expressed ribosomal protein genes, and characterize them in the context of other non-coding RNAs regulated by chromatin and transcription related factors.