GSM3024797[Accession] - GEO DataSets

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Items: 4

Select item 2001111751.

Perturbations of PI3K/AKT, RAS/ERK, WNT/B-catenin networks in leukocytes are linked to ASD genetics and fetal origins of autism

(Submitter supplied) Hundreds of genes are implicated in autism spectrum disorder (ASD) but the mechanisms through which they contribute to ASD pathophysiology remain elusive. Here, we analyzed leukocyte transcriptomics from 1-4 year-old male toddlers with ASD or typical development from the general population. We discovered a perturbed gene network that includes genes highly expressed during fetal brain development and which is dysregulated in hiPSC-derived neuron models of ASD. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
141 Samples

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Series

Accession:: GSE111175

ID:: 200111175

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001111762.

Transcriptional organization of autism spectrum disorder

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
288 Samples

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Series

Accession:: GSE111176

ID:: 200111176

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000105583.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...