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Items: 4

1.

Perturbations of PI3K/AKT, RAS/ERK, WNT/B-catenin networks in leukocytes are linked to ASD genetics and fetal origins of autism

(Submitter supplied) Hundreds of genes are implicated in autism spectrum disorder (ASD) but the mechanisms through which they contribute to ASD pathophysiology remain elusive. Here, we analyzed leukocyte transcriptomics from 1-4 year-old male toddlers with ASD or typical development from the general population. We discovered a perturbed gene network that includes genes highly expressed during fetal brain development and which is dysregulated in hiPSC-derived neuron models of ASD. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
141 Samples
Download data: TXT
Series
Accession:
GSE111175
ID:
200111175
2.

Transcriptional organization of autism spectrum disorder

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
288 Samples
Download data
Series
Accession:
GSE111176
ID:
200111176
3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2946 Series
4 Related Platforms
105286 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

Z2D8Q

Organism:
Homo sapiens
Source name:
leukocyte transcriptome
Platform:
GPL10558
Series:
GSE111175 GSE111176
Download data
Sample
Accession:
GSM3024817
ID:
303024817
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