GSM317335[Accession] - GEO DataSets

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Items: 4

Select item 2000126431.

Transcription profiling of myotubes from patients with type 2 diabetes

(Submitter supplied) Microarray-based studies of skeletal muscle from patients with type 2 diabetes and high-risk individuals have demonstrated that insulin resistance and reduced mitochondrial biogenesis co-exist early in the pathogenesis of type 2 diabetes independent of hyperglycaemia and obesity. It is unknown whether reduced mitochondrial biogenesis or other transcriptional alterations co-exist with impaired insulin-responsiveness in primary human muscle cells from patients with type 2 diabetes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3681
Platform:: GPL8300
20 Samples

Download data: CEL

Series

Accession:: GSE12643

ID:: 200012643

Select item 36812.

Type 2 diabetes: myotube

Analysis of myotube cell lines established from type 2 diabetes (T2D) subjects. Insulin resistance and reduced mitochondrial biogenesis coexist early in T2D pathogenesis independent of hyperglycemia and obesity. Results provide insight into the effect of T2D on developing skeletal muscle cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL8300
Series:: GSE12643
20 Samples

Download data: CEL

DataSet

Accession:: GDS3681

ID:: 3681

Select item 1000083003.

[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes. more...