GSM328673[Accession] - GEO DataSets

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Items: 4

Select item 2000131221.

The Effect of Translocation-Induced Nuclear Re-organization on Gene Expression

(Submitter supplied) To study the effect of balanced chromosomal rearrangements on gene expression, we compared the transcriptomes of cell lines from control and t(11;22)(q23;q11) individuals. This translocation between chromosomes 11 and 22 is the only recurrent constitutional non-Robertsonian translocation in humans. The number of differentially expressed transcripts between the translocated and control cohort is significantly higher than that observed between control samples alone, suggesting that balanced rearrangements have a greater effect on gene expression than normal variation. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4264
Platform:: GPL570
26 Samples

Download data: CEL

Series

Accession:: GSE13122

ID:: 200013122

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 42642.

Balanced and unbalanced chromosomal translocations: lymphoblastoid cell lines

Analysis of lymphoblastoid cell lines established from individuals with the t(11;22)(q23;q11)-balanced translocation (carriers) or the +der(22)t(11;22)(q23;q11) karyotype (Emanuel syndrome patients). Results provide insight into the effect of balanced chromosomal rearrangements on the transcriptome.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 24 age, 3 disease state, 2 gender, 3 genotype/variation, 8 other sets

Platform:: GPL570
Series:: GSE13122
26 Samples

Download data: CEL

DataSet

Accession:: GDS4264

ID:: 4264

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...