GSM3294943[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001287451.

Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms
210 Samples

Download data: BED, NARROWPEAK

Series

Accession:: GSE128745

ID:: 200128745

PubMed Full text in PMC Similar studies

Select item 2001174462.

Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas [RNA-Seq]

(Submitter supplied) Epigenetic alterations are recurrently observed in cancer and are the subject of active therapeutic investigations. Midline high-grade gliomas (HGGs) are deadly brain tumors characterized by lysine-to-methionine substitutions at position 27 in histone 3 (H3) variants (denoted H3K27M), which are core components of the nucleosome. H3K27M, the first event in midline HGG development, results in a drastic loss of the repressive histone mark H3K27 tri-methylation (H3K27me3), and a notable increase in H3K27 acetylation (H3K27ac), a mark associated with active chromatin and cellular identity. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL16791 GPL11154 GPL20301
96 Samples

Download data: TXT

Series

Accession:: GSE117446

ID:: 200117446

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000167913.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12223 Series
349703 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3032949434.

Organism:: Homo sapiens

Source name:: Tumor-derived cell-line

Platform:: GPL16791
Series:: GSE117446 GSE128745

Sample

Accession:: GSM3294943

ID:: 303294943

SRA Run Selector

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