GSM334357[Accession] - GEO DataSets

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Items: 3

Select item 2000132551.

Gene Expression Profiles in Peripheral Blood Mononuclear Cells Can Distinguish Patients with NonSmall Cell Lung Cancer.

(Submitter supplied) We report a 29-gene diagnostic signature, which distinguishes individuals with NSCLC from controls with non-malignant lung disease with 91% Sensitivity, 79% Specificity and a ROC AUC of 92%. Accuracy on an independent set of 18 NSCLC samples from the same location was 79%. Samples from an independent location including 12 stage 1 NSCLC and 15 controls, achieved an accuracy of 74%. A study of 18 paired samples taken pre and post surgery shows that the PBMC associated “cancer” signature is significantly reduced after tumor removal, supporting the hypothesis that the signature detected in pre-surgery samples is a response to the presence of the tumor.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6102
291 Samples

Download data: TXT

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Accession:: GSE13255

ID:: 200013255

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000061022.

Illumina human-6 v2.0 expression beadchip

(Submitter supplied) Researchers can generate whole genome expression profiles for multiple samples on a single BeadChip. Researchers can profile six or eight samples perBeadChip, with more than 48,000 transcript probes per sample using the Human-6 v2 beadchip. Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...