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Items: 3

1.

Iron and Heme Coordinate Erythropoiesis through HRI-Mediated Regulation of Protein Translation and Gene Expression

(Submitter supplied) Iron and heme play central roles in red blood cell production. However, the mechanisms by which iron and heme levels coordinate erythropoiesis remain incompletely understood. HRI is a heme-regulated kinase that controls translation by phosphorylating eIF2a. Here, we investigate the global impact of iron, heme and HRI on protein translation in vivo in murine primary erythroblasts using ribosome profiling. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL13112
21 Samples
Download data: TXT
Series
Accession:
GSE119365
ID:
200119365
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

ribo_seq_wt_minus_r1

Organism:
Mus musculus
Source name:
Fetal liver
Platform:
GPL13112
Series:
GSE119365
Download data: TXT
Sample
Accession:
GSM3371792
ID:
303371792
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