GSM348119[Accession] - GEO DataSets

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Items: 3

Select item 2000138471.

Role of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium

(Submitter supplied) Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonella effector proteins SipA, SopA, SopB, SopD, and SopE2 into the host epithelial cell cytoplasm. These five effector proteins act in concert to induce fluid secretion and transcription of C-X-C chemokines, which serve to recruit PMNs to the intestine. more...

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL2853
84 Samples

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Accession:: GSE13847

ID:: 200013847

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000028532.

UIUC Bos taurus 13.2K 70-mer oligoarray

(Submitter supplied) The 13,257 oligos used in this microarray were obtained from normalized and subtracted cattle placenta and spleen cDNA libraries and based upon the earlier cDNA array platform GPL2864 (Everts et al., 2005 Vet. Immunol. Immunopathol. 105:235-245) and subtracted cDNA libraries created from embryonic (day 36 and day 64) and extra-embryonic (day 14 to 25) tissues (NCBI libraries 15993,15993, and 17188). more...