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Items: 4

1.

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

(Submitter supplied) The enteric nervous system (ENS) predominantly originates from vagal neural crest cells (VNC) that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Using an EdnrB enhancer, we generated a comprehensive temporal map of the chromatin and transcriptional landscape of VNC in the avian model, revealing three VNC cell clusters (neural, neurogenic and mesenchymal), each predetermined epigenetically prior to neural tube delamination. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19787
67 Samples
Download data: MTX, TSV
Series
Accession:
GSE125711
ID:
200125711
2.

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages [CRISPR RNA-seq]

(Submitter supplied) The enteric nervous system (ENS) predominantly originates from vagal neural crest cells (VNC) that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Using an EdnrB enhancer, we generated a comprehensive temporal map of the chromatin and transcriptional landscape of VNC in the avian model, revealing three VNC cell clusters (neural, neurogenic and mesenchymal), each predetermined epigenetically prior to neural tube delamination. more...
Organism:
Gallus gallus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19787
16 Samples
Download data: TXT
Series
Accession:
GSE125710
ID:
200125710
3.

Illumina NextSeq 500 (Gallus gallus)

Platform
Accession:
GPL19787
ID:
100019787
4.

tfap2b_KO_RNA_R1

Organism:
Gallus gallus
Source name:
tfap2b_KO_RNA_R1
Platform:
GPL19787
Series:
GSE125710 GSE125711
Download data
Sample
Accession:
GSM3580771
ID:
303580771
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Supplemental Content

db=gds|term=GSM3580771[Accession]|query=1|qty=2|blobid=MCID_674c47e2d826084038503f12|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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