GSM3781193[Accession] - GEO DataSets

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Items: 4

Select item 2001271771.

Progressive dosage compensation during Drosophila embryogenesis is reflected by gene arrangement on the X chromosome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL19951
96 Samples

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Series

Accession:: GSE127177

ID:: 200127177

PubMed Full text in PMC Similar studies

Select item 2001271752.

Progressive dosage compensation during Drosophila embryogenesis is reflected by gene arrangement on the X chromosome [ChIP-seq]

(Submitter supplied) In D. melanogaster males, X chromosome monosomy is compensated by chromosome-wide transcription activation. We found that complete dosage compensation during embryogenesis takes surprisingly long. Although the activating Dosage Compensation Complex (DCC) associates with the chromosome and acetylates histone H4 early, many genes are not compensated. Acetylation levels on gene bodies continue to increase for several hours after gastrulation in parallel with progressive compensation. more...