GSM398015[Accession] - GEO DataSets

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Items: 3

Select item 2000158451.

Knockdown of STAT1 in SCC61 tumor xenografts leads to alterations in the expression of energy metabolic pathways

(Submitter supplied) Background: Signal Transducer and Activator of Transcription 1 (STAT1) has traditionally been regarded as a transmitter of interferon signaling and a pro-apoptotic tumor suppressor. Recent data have identified new functions of STAT1 associated with tumorigenesis and resistance to genotoxic stress, including ionizing radiation (IR) and chemotherapy. To investigate the mechanisms contributing to the tumorigenic functions of STAT1, we performed a combined transcriptomic-proteomic expressional analysis and found that STAT1 is associated with regulation of energy metabolism. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
8 Samples

Download data: CEL

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Accession:: GSE15845

ID:: 200015845

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000062442.

[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site